Fell-Muir Lecture: Proteoglycans and more--from molecules to biology.

@article{Heinegrd2009FellMuirLP,
  title={Fell-Muir Lecture: Proteoglycans and more--from molecules to biology.},
  author={Dick Heineg{\aa}rd},
  journal={International journal of experimental pathology},
  year={2009},
  volume={90 6},
  pages={575-86}
}
In this article the organization and functional details of the extracellular matrix, with particular focus on cartilage, are described. All tissues contain a set of molecules that are arranged to contribute structural elements. Examples are fibril-forming collagens forming major fibrillar networks in most tissues. The assembly process is regulated by a number of proteins (thrombospondins, LRR-proteins, matrilins and other collagens) that can bind to the collagen molecule and in many cases… CONTINUE READING

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