Feline sarcoma virus induced in vitro progression from premalignant to neoplastic transformation of human diploid cells

@article{Milo1980FelineSV,
  title={Feline sarcoma virus induced in vitro progression from premalignant to neoplastic transformation of human diploid cells},
  author={George E. Milo and Richard g. Olsen and Steven E. Weisbrode and John A. McCloskey},
  journal={In Vitro},
  year={1980},
  volume={16},
  pages={813-822}
}
SummaryHuman diploid cells morphologically transformed by feline sarcoma virus were serially propagated under selective cell culture conditions. When injected into nude mice prior to passage in soft agar (0.35%), morphologically transformed cells did not produce tumors. However, when propagated under selective cell culture conditions, transformed cells grew in soft agar and, when injected subcutaneously into the subcapsular region of the nμ/nμ mice, produced neoplastic nodules… CONTINUE READING

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