• Biology, Medicine
• Published in
  The American journal of…
  1993

Feline immunodeficiency virus predisposes cats to acute generalized toxoplasmosis.

@article{Davidson1993FelineIV,
  title={Feline immunodeficiency virus predisposes cats to acute generalized toxoplasmosis.},
  author={M. G. Davidson and James B Rottman and Robert V. English and Michael R Lappin and Mary B. Tompkins},
  journal={The American journal of pathology},
  year={1993},
  volume={143 5},
  pages={
          1486-97
        }
}

• M. G. Davidson, James B Rottman, +2 authors Mary B. Tompkins

This study was designed to examine the effects of a pre-existing, clinically asymptomatic feline immunodeficiency virus (FIV) infection on a primary challenge with Toxoplasma gondii. Parenteral challenge of FIV-infected cats with tachyzoites of the ME49 strain of T. gondii caused a precipitous drop in all lymphocytes (CD4+, CD8+, and B cells) and generalized severe toxoplasmosis. The predominant postmortem lesions included acute and often fatal interstitial pneumonia, dominated histologically… CONTINUE READING

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