Feline analgesia following central administration of opioids.


Activity of opioids in cats was assessed by employing the tail-flick method. Microinjection of morphine (100 micrograms) or etorphine (2.5 micrograms) into the ventrolateral periaqueductal gray (VLPAG) region resulted in significant analgesia. Smaller doses of morphine (10 and 50 micrograms) or etorphine (0.62 and 1.25 micrograms) were without significant… (More)


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