Feigrisolides A, B, C and D, new lactones with antibacterial activities from Streptomyces griseus.

@article{Tang2000FeigrisolidesAB,
  title={Feigrisolides A, B, C and D, new lactones with antibacterial activities from Streptomyces griseus.},
  author={Y. Q. Tang and I. Sattler and R. Thiericke and S. Grabley and X. Z. Feng},
  journal={The Journal of antibiotics},
  year={2000},
  volume={53 9},
  pages={
          934-43
        }
}
Four new lactone compounds, named feigrisolides A to D (1 to 4), have been isolated from Streptomyces griseus. The chemical structures were determined by detail analysis of their spectroscopic data and chemical transformations. Structurally, the feigrisolides A (1) and B (2) are hepta-lactones, feigrisolide C (3) and D (4) are 16-membered macrodiolides. Biological studies showed that feigrisolide B (2) exhibited strong antibacterial, as well as medium cyctotoxic, and antiviral activities… Expand
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