Feelings of warmth correlate with neural activity in right anterior insular cortex

  title={Feelings of warmth correlate with neural activity in right anterior insular cortex},
  author={H{\aa}kan Olausson and Jonathan Charron and Serge Marchand and Chantal Villemure and Irina A. Strigo and M. Catherine Bushnell},
  journal={Neuroscience Letters},

Functional organization of the human anterior insular cortex

Memory Traces of Pain in Human Cortex

It is proposed that SI/PPC plays a role in the short-term retention of spatial and intensity aspects of noxious stimuli and that aIC activation during memory trials is consistent with the integration of sensory and cognitive components of pain perception.

Neural correlates of ambient thermal sensation: An fMRI study

Functional magnetic resonance imaging was employed and ambient temperature was manipulated during brain measurement to independently explore the neural correlates of thermal sensation and comfort and no significant correlations were observed between brain activation and thermal comfort.

BOLD Responses in Somatosensory Cortices Better Reflect Heat Sensation than Pain

The results indicate that heat intensity is encoded by the somatosensory cortices, and that pain evaluation may either arise from multimodal evaluative processes, or is a distributed process.

Neuroimaging of pleasantness and unpleasantness induced by thermal stimuli

There is a gap in the understanding of hedonics related to regional brain activations and it would appear that thermoregulatory regions are widely distributed throughout the hemispheres of the human brain.

Human Brain Activity Related to the Tactile Perception of Stickiness

The human neural correlates of the tactile perception of stickiness are unveiled and may contribute to broadening the understanding of neural mechanisms associated with tactile perception.

Anatomical and functional enhancements of the insula after loss of large primary somatosensory fibers.

Plasticity in networks involving the insular cortex following denervation of large-diameter somatosensory afferents is demonstrated and could be related to the patient's use of C-fiber touch and temperature information in conjunction with visual information to navigate her environment.

Functional connectivity of the insula in the resting brain




Thermosensory activation of insular cortex

Using positron emission tomography, it is found contralateral activity correlated with graded cooling stimuli only in the dorsal margin of the middle/posterior insula in humans, which supports the proposal that central pain results from loss of the normal inhibition of pain by cold.

Neural systems supporting interoceptive awareness

In right anterior insular/opercular cortex, neural activity predicted subjects' accuracy in the heartbeat detection task and local gray matter volume correlated with both interoceptive accuracy and subjective ratings of visceral awareness.

Perceptual illusion of "paradoxical heat" engages the insular cortex.

Using the technique of percept-related functional MRI, a region of the right insular cortex specifically activated when subjects perceive a heat sensation in their right hand even though their skin temperature is cool or at neutral is found.

Functional MRI study of thalamic and cortical activations evoked by cutaneous heat, cold, and tactile stimuli.

Functional magnetic resonance imaging is used to locate discrete regions of the thalamus, insula, and second somatosensory cortex modulated during innocuous and noxious thermal stimulation and provides support for a role of the anterior insula and S2 in the perception of pain; whereas the posterior insula appears to be involved in tactile and innocuous temperature perception.

Neurophysiology and Functional Neuroanatomy of Pain Perception

  • A. SchnitzlerM. Ploner
  • Biology, Psychology
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
  • 2000
The authors review the evidence on which the proposed relationship between cortical areas, pain-related neural activations, and components of pain perception is based.

Evidence of a specific spinal pathway for the sense of warmth in humans.

The results support the existence of slow-conducting second-order neurons specific for the sense of warmth in the central nervous system, and study the cortical areas involved in the cerebral processing of warm and nociceptive inputs.

Functional imaging of an illusion of pain

TOUCHING warm and cool bars that are spatially interlaced produces a painful burning sensation resembling that caused by intense, noxious cold. We demonstrated previously that this thermal grill

Cortical activation by tactile and painful stimuli in hemispherectomized patients.

The findings from tactile stimulation of the nonparetic leg, that the activation was similar to the contralateral activation in normals, suggest that tactile information processing in the hemisphere contralsateral to the stimulation is independent of the corpus callosum.