Feeding the immune system

  title={Feeding the immune system},
  author={Philip C. Calder},
  journal={Proceedings of the Nutrition Society},
  pages={299 - 309}
  • P. Calder
  • Published 21 May 2013
  • Medicine, Biology
  • Proceedings of the Nutrition Society
A well-functioning immune system is key to providing good defence against pathogenic organisms and to providing tolerance to non-threatening organisms, to food components and to self. The immune system works by providing an exclusion barrier, by identifying and eliminating pathogens and by identifying and tolerating non-threatening sources of antigens, and by maintaining a memory of immunological encounters. The immune system is complex involving many different cell types distributed throughout… 

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  • 2020
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The effects of a range different dietary components on anti-infective innate as well as adaptive immune responses are described and mechanisms by which they may interact with the immune system in the respiratory tract are proposed.

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A Workshop held in February 2006 considered recent findings in the areas of oral tolerance, routes of sensitization to allergens and factors affecting the development of atopic disease; factors influencing the maturation of dendritic cells and thedevelopment of regulatory T cells; the influence of gut microflora on immunity, allergic sensitization and infectious disease; the role of nutrition in preventing necrotizing enterocolitis.

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Parts of zinc biology of the immune system are explored and a biological basis for the altered host resistance to infections observed during zinc deficiency and supplementation is attempted.

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Vitamin A deficiency diminishes antibody-mediated responses directed by Th2 cells, although some aspects of Th1-mediated immunity are also diminished, presumably account for the increased mortality seen in vitamin A-deficient infants, young children, and pregnant women in many areas of the world today.

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  • 2003
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The immune response to gastrointestinal infection, the mechanisms that the gastrointestinal system uses to absorb intraluminal iron, and the critical role iron plays in the infectious process are described.

Clinical relevance of age-related immune dysfunction.

  • S. Castle
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    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2000
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Changes in gene expression for cytokines, DNA repair enzymes, zinc transporters, signaling molecules, etc., suggest that cells of the immune system are attempting to adapt to the stress of suboptimal zinc.

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Overall the results indicate that beta2-1 fructans are able to modulate some aspects of immune function, to improve the host's ability to respond successfully to certain intestinal infections, and to modify some inflammatory conditions.

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  • E. Burns
  • Biology
    The journal of nutrition, health & aging
  • 2004
A variety of changes are observed in the immune system in both animals and humans with increasing age. There is a decline in the functional capacity of the cell populations that mount generalized and