Feeding stimulated by very low doses of d-amphetamine administered systemically or by microinjection into the striatum

@article{Winn1982FeedingSB,
  title={Feeding stimulated by very low doses of d-amphetamine administered systemically or by microinjection into the striatum},
  author={Philip Winn and Sarah F. Williams and Lieselotte Herberg},
  journal={Psychopharmacology},
  year={1982},
  volume={78},
  pages={336-341}
}
The effects of d-amphetamine over a wide range of doses (0.125–4.0 mg/kg IP) on rat unconditioned behaviour were examined in the presence of food and water (experiment 1), in their absence (experiment 2) and after microinjection (2.0 μg in 0.5 μl) directly into the striatum (experiment 3). In experiment 1 very low doses (0.125 and 0.25 mg/kg) stimulated the intake of food, but not water, and higher doses produced locomotor hyperactivity, rearing, stereotyped sniffing and anorexia. In experiment… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

The enigma of the basal ganglia and movement

CD Marsden
  • Trend Neurosci
  • 1980
VIEW 1 EXCERPT

Hyperactivity induced by intra - accumbens dopamine : Action and interactions of neuroleptic , cholinomimetic and cholinolytic agents

B Costall, Hui SCG, RJ Naylor
  • Neuropharmacology
  • 1979