Feedback in the Contractile Mechanism of the Frog Heart

  • Emil Bozler
  • Published 1972 in The Journal of general physiology


Shortening causes a transient decrease, extension an increase, in activity during contractures of the frog ventricle induced by high Ca or by isosmotic K solution. This is shown by the fact that, after the immediate passive shortening, the muscle is extended under isotonic conditions when the load is diminished, and that under isometric conditions quick… (More)


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