Feedback dynamics and cell function: Why systems biology is called Systems Biology.

@article{Wolkenhauer2005FeedbackDA,
  title={Feedback dynamics and cell function: Why systems biology is called Systems Biology.},
  author={Olaf Wolkenhauer and Mihajlo D. Mesarovic},
  journal={Molecular bioSystems},
  year={2005},
  volume={1 1},
  pages={14-6}
}
A new paradigm, like Systems Biology, should challenge the way research has been conducted previously. This Opinion article aims to present Systems Biology, not as the application of engineering principles to biology but as a merger of systems- and control theory with molecular- and cell biology. In our view, the central dogma of Systems Biology is that it is system dynamics that gives rise to the functioning and function of cells. The concepts of feedback regulation and control of pathways and… CONTINUE READING