FecalSeq : methylation-based enrichment for noninvasive population genomics from feces

@inproceedings{Chiou2015FecalSeqM,
  title={FecalSeq : methylation-based enrichment for noninvasive population genomics from feces},
  author={Kenneth L Chiou and Christina M. Bergey},
  year={2015}
}
We developed an inexpensive methylation-based capture method for enriching host DNA from noninvasively obtained fecal samples. We demonstrate that the enrichment is robust, efficient, and compatible with downstream library preparation methods, including complexity-reduction approaches for massively parallel sequencing. Because feces are widely available and convenient to collect, our method empowers researchers to explore genomic-scale population-level questions in organisms for which invasive… CONTINUE READING