Fecal microbiota transplantation through mid-gut for refractory Crohn's disease: safety, feasibility, and efficacy trial results.

@article{Cui2015FecalMT,
  title={Fecal microbiota transplantation through mid-gut for refractory Crohn's disease: safety, feasibility, and efficacy trial results.},
  author={Bota Cui and Qiang Feng and Honggang Wang and Min Wang and Zhaoyuan Peng and Pan Li and Guangming Huang and Zeng Liu and Ping Wu and Zhining Fan and Guozhong Ji and Xin Wang and Kaichun Wu and Dai-ming Fan and Faming Zhang},
  journal={Journal of gastroenterology and hepatology},
  year={2015},
  volume={30 1},
  pages={51-8}
}
BACKGROUND AND AIM The gut microbiota plays a pivotal role in the intestinal diseases. Fecal microbiota transplantation (FMT) might be a rescue therapy for refractory inflammatory bowel disease. This study aimed to evaluate the safety, feasibility, and efficacy of FMT through mid-gut for refractory Crohn's disease (CD). METHODS We established standardized laboratory protocol and clinical work flow for FMT. Only refractory CD patients with Harvey-Bradshaw Index (HBI) score ≥ 7 were enrolled… CONTINUE READING
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