Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome

@article{NagySzakal2017FecalMP,
  title={Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome},
  author={D. Nagy‐Szakal and B. L. Williams and N. Mishra and X. Che and Bohyun Lee and L. Bateman and N. Klimas and A. Komaroff and S. Levine and J. Montoya and D. Peterson and Devi Ramanan and K. Jain and M. L. Eddy and M. Hornig and W. Lipkin},
  journal={Microbiome},
  year={2017},
  volume={5}
}
BackgroundMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by unexplained persistent fatigue, commonly accompanied by cognitive dysfunction, sleeping disturbances, orthostatic intolerance, fever, lymphadenopathy, and irritable bowel syndrome (IBS). The extent to which the gastrointestinal microbiome and peripheral inflammation are associated with ME/CFS remains unclear. We pursued rigorous clinical characterization, fecal bacterial metagenomics, and plasma immune… Expand

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Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons
Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS
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