Fecal excretion of alpha 2-macroglobulin: a novel marker for disease activity in patients with inflammatory bowel disease.

@article{Becker1999FecalEO,
  title={Fecal excretion of alpha 2-macroglobulin: a novel marker for disease activity in patients with inflammatory bowel disease.},
  author={Klaus Becker and Claus Niederau and Thomas J. Frieling},
  journal={Zeitschrift fur Gastroenterologie},
  year={1999},
  volume={37 7},
  pages={
          597-605
        }
}
BACKGROUND Quantification of fecal alpha 1-antitrypsin (AAT) excretion is established for estimation of enteric protein loss and assessment of disease activity in inflammatory bowel disease (IBD). In contrast, little is known about prevalence, course, and clinical significance of intestinal leakage of larger-size serum antiproteinases in these disorders. SUBJECTS AND METHODS Firstly, 23 IBD patients (Crohn's disease, CD, n = 17, and ulcerative colitis, UC, n = 6) were examined at 34… CONTINUE READING