Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial.

  title={Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial.},
  author={Paul Moayyedi and Michael G. Surette and Peter T. Kim and Josie Libertucci and Melanie Wolfe and Catherine Onischi and David Armstrong and John K. Marshall and Zain A Kassam and Walter Reinisch and Christine H. Lee},
  volume={149 1},
BACKGROUND & AIMS Ulcerative colitis (UC) is difficult to treat, and standard therapy does not always induce remission. Fecal microbiota transplantation (FMT) is an alternative approach that induced remission in small series of patients with active UC. We investigated its safety and efficacy in a placebo-controlled randomized trial. METHODS We performed a parallel study of patients with active UC without infectious diarrhea. Participants were examined by flexible sigmoidoscopy when the study… 

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