Febuxostat: drug review and update.

  title={Febuxostat: drug review and update.},
  author={Harmanjot Kaur Grewal and J. R. Mora Mart{\'i}nez and Luis Rolan Espinoza},
  journal={Expert opinion on drug metabolism & toxicology},
  volume={10 5},
INTRODUCTION Gouty arthritis and hyperuricemia have ailed humans for centuries. Recent advances in understanding of the mechanism(s) of their development have changed our perception of the disease process. Despite these gains, the treatment options available are limited. The FDA approval of febuxostat for the treatment of hyperuricemia in gout has been a significant step forward. Since its approval in 2009, febuxostat has proven to be safe and efficacious although concerns remain regarding its… CONTINUE READING

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