Febrile temperatures can synchronize the growth of Plasmodium falciparum in vitro

@article{Kwiatkowski1989FebrileTC,
  title={Febrile temperatures can synchronize the growth of Plasmodium falciparum in vitro},
  author={Dominic P Kwiatkowski},
  journal={The Journal of Experimental Medicine},
  year={1989},
  volume={169},
  pages={357 - 361}
}
To investigate the possibility that the host fever response in malaria may affect parasite development, we studied the effect of temperature on Plasmodium falciparum in erythrocytic culture in vitro. Growth was markedly suppressed at 40 degrees C compared with 37 degrees C, due to disruption of the second half of the 48-h erythrocytic cycle. However, young intraerythrocytic parasites, which are highly exposed to fever during natural infection, appeared to develop normally at 40 degrees C… CONTINUE READING

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