Febrile seizures and mesial temporal sclerosis

@article{Tarkka2003FebrileSA,
  title={Febrile seizures and mesial temporal sclerosis},
  author={Rita Tarkka and E. P{\"a}{\"a}kk{\"o} and Juhani Pyhtinen and Matti Uhari and Heikki M J Rantala},
  journal={Neurology},
  year={2003},
  volume={60},
  pages={215 - 218}
}
Objective: To determine whether febrile seizures cause mesial temporal sclerosis (MTS), the occurrence of MTS was evaluated in an unselected series of patients with febrile seizures. Methods: Twenty-four patients with a prolonged first febrile seizure, 8 with an unprovoked seizure after the first febrile seizure, and 32 age-, sex-, and handedness-matched control subjects with a single simple febrile seizure without later unprovoked seizures were selected from 329 febrile seizure patients… Expand
Mesial temporal sclerosis
TLDR
Clinical studies are suggestive of the occurrence of lesions in children with prolonged febrile seizures, and specific surgical procedures including anterior temporal lobectomy tailored towards resection of the mesial temporal lesion have a much higher rate of success in intractable epilepsy patients. Expand
Hippocampal alterations in children with temporal lobe epilepsy with or without a history of febrile convulsions: evaluations with MR volumetry and proton MR spectroscopy.
TLDR
Children with Tle and early history of FC tend to have lower hippocampal volumes and NAA/(Cr + Cho) ratios than do TLE children without FC history, and the TLE + FC group seems to have increased vulnerability of the contralateral hippocampus as compared with TLE group. Expand
Drug-responsive versus drug-refractory mesial temporal lobe epilepsy: a single-center prospective outcome study
TLDR
This prospective study shows that sleep activation on EEG, ictal automatisms, occurrence of focal to bilateral tonic-clonic seizures, and increased number of tried AEDs are negative prognostic factors. Expand
Hippocampal MRI signal hyperintensity after febrile status epilepticus is predictive of subsequent mesial temporal sclerosis.
TLDR
MRI findings of a markedly hyperintense hippocampus in children with febrile status epilepticus was highly associated with subsequent mesial temporal sclerosis. Expand
Febrile seizures: the role of intermittent prophylaxis
TLDR
It is widely recognized now that the cumulative evidence from randomized controlled studies has revealed that febrile seizures mostly are self-limited benign conditions with good outcome. Expand
Isolated febrile seizures are not associated with structural abnormalities of the limbic system
TLDR
It is suggested that structural abnormalities of the hippocampus and limbic white matter that have been demonstrated in TLE are not associated with isolated CFS. Expand
Correlation of Electroencephalography and Magnetic Resonance Imaging in Patients with Mesial Temporal Sclerosis.
TLDR
It is suggested that, when correlated with MRI, EEG is a non-invasive and easy method to identify lateralization findings in patients with mesial temporal sclerosis. Expand
Recent Advances in Febrile Seizures
  • R. Mittal
  • Medicine
  • The Indian Journal of Pediatrics
  • 2014
TLDR
After a febrile seizure, it is important to rule out CNS infection and the decision to perform a lumbar puncture should be based on the clinical condition of the child. Expand
[Frequency of recurrent convulsions after a first febrile seizure: two-year observation results].
TLDR
The frequency of convulsion recurrence was established through the retrospective study with regard to age, type of recurrence, and applied prophylaxis in children in Tuzla Canton in a two-year period after the first febrile convulsion. Expand
Febrile seizures C h ild h ealth
INTRODUCTION: Simple febrile seizures are generalised in onset and have a brief duration. The American Academy of Pediatrics defines this brief duration to be <15 minutes; whereas, in the UK, aExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 19 REFERENCES
Bilateral reductions in hippocampal volume in adults with epilepsy and a history of febrile seizures
TLDR
Results suggest that a history of febrile seizures is associated with the finding of a smaller hippocampus on the side ipsilateral to the subsequent temporal lobe focus whereas chronic factors seem to be be related to pathology contralateral to the seizure focus. Expand
Magnetic resonance imaging findings within 5 days of status epilepticus in childhood.
TLDR
A systematic longitudinal study is required to characterize the evolution of these abnormalities and to determine whether any patient develops MTS, as well as to investigate whether generalized status epilepticus is associated with brain abnormalities within 5 days of the acute event. Expand
Hippocampal malformation as a cause of familial febrile convulsions and subsequent hippocampal sclerosis. 1998.
TLDR
A subtle, pre-existing hippocampal malformation that may facilitate febrile convulsions and contribute to the development of subsequent HS is suggested. Expand
Quantitative MRI hippocampal volumes: association with onset and duration of epilepsy, and febrile convulsions in temporal lobectomy patients
TLDR
Investigation of relationships between preoperatively acquired MRI-based hippocampal volumes, seizure disorder onset and duration, and early childhood febrile convulsions suggest that hippocampal atrophy remains stable over the duration of temporal lobe onset seizure disorders, and is associated with early onset of recurrent seizures in left temporal patients. Expand
Hippocampal sclerosis in epilepsy and childhood febrile seizures
TLDR
Investigation of patients with drug-resistant epilepsy by high-resolution volumetric magnetic resonance imaging shows that hippocampal sclerosis is strongly associated with a history of CFS, but it is not clear whether this is a causal relationship. Expand
Temporal lobe seizures: lateralization with MR volume measurements of the hippocampal formation.
TLDR
A retrospective magnetic resonance (MR) imaging study was performed in 41 right-handed patients with presumed mesial sclerosis who underwent surgery for medically intractable, complex partial seizures of temporal lobe origin, finding DHF measurements to be 76% sensitive and 100% specific for correct seizure lateralization. Expand
Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsions
TLDR
Evidence of preexisting hippocampal abnormalities in several infants and electrographical temporal lobe seizure activity in 1 suggests the possibility that CFCs actually originated in the temporal lobes in some patients. Expand
Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients
TLDR
Whether it is possible to diagnose specific epilepsy syndromes promptly by use of standard clinical methods, electroencephalography (EEG) and magnetic resonance imaging (MRI) and unclassified diagnosis is studied. Expand
Bilateral Hippocampal Volume Loss in Patients with a History of Encephalitis or Meningitis
Volumetric analysis of high‐quality magnetic resonance imaging (MRI) scans identifies asymmetric hippocampal atrophy in most patients with temporal lobe epilepsy. However, bilateral hippocampalExpand
Magnetic resonance image–based hippocampal volumentry: Correlation with outcome after temporal lobectomy
TLDR
MRI‐based study of hippocampal formation volume is regarded as a noninvasive surrogate for the identification of moderate or severe mesial temporal sclerosis and is a useful adjunct in a multidisciplinary, preoperative epilepsy evaluation when T2‐weighted MRIs do not reveal an epileptogenic mass lesion. Expand
...
1
2
...