Febrile reactions to platelet transfusion: the effect of increased interleukin 6 levels in concentrates prepared by the platelet-rich plasma method.

@article{Muylle1996FebrileRT,
  title={Febrile reactions to platelet transfusion: the effect of increased interleukin 6 levels in concentrates prepared by the platelet-rich plasma method.},
  author={Ludo Muylle and Emiel F.M. Wouters and Marc E. Peetermans},
  journal={Transfusion},
  year={1996},
  volume={36 10},
  pages={
          886-90
        }
}
BACKGROUND A relation between febrile reactions to platelet transfusion and high cytokine levels in platelet concentrates (PCs) was found previously. The levels of cytokines such as interleukin (IL)-6 are related to the while cell content of the PC during storage. Therefore, early removal of white cells should prevent reactions. STUDY DESIGN AND METHODS This prospective study was set up to compare methods for the preparation of random PCs, the platelet-rich plasma method (PRP-PCs), which… CONTINUE READING

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