Febrile neutropenia

  title={Febrile neutropenia},
  author={Jean Klastersky},
  journal={Current Opinion in Oncology},
  • J. Klastersky
  • Published 1 July 1993
  • Medicine
  • Current Opinion in Oncology
Severe neutropenia and its related infectious complications remain a permanent threat for patients receiving intensive chemotherapy, especially in the context of bone marrow transplantation. Chemoprophylaxis and use of colony-stimulating factors have altered the severity of the clinical picture in a favorable direction: neutropenia can be shortened, and gram-negative infection can be made less frequent; neither can be yet abolished. Early therapy, eg, empiric combination treatment, remains the…