Features of chromosomal abnormalities in spontaneous abortion cell culture failures detected by interphase FISH analysis

@article{Lebedev2004FeaturesOC,
  title={Features of chromosomal abnormalities in spontaneous abortion cell culture failures detected by interphase FISH analysis},
  author={Igor N. Lebedev and Nadezhda V Ostroverkhova and Tatyana V Nikitina and Natalia N. Sukhanova and Sergey A Nazarenko},
  journal={European Journal of Human Genetics},
  year={2004},
  volume={12},
  pages={513-520}
}
Cytogenetic analysis of reproductive wastage is an important stage in understanding the genetic background of early embryogenesis. The results of conventional cytogenetic studies of spontaneous abortions depend on tissue culturing and are associated with a significant cell culture failure rate. We performed interphase dual-colour FISH analysis to detect chromosomal abnormalities in noncultured cells from two different tissues–cytotrophoblast and extraembryonic mesoderm–of 60 first-trimester… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 34 references

Similar Papers

Loading similar papers…