Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data

@article{Corcoran2009FeaturesOM,
  title={Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data},
  author={David L. Corcoran and Kusum V. Pandit and Ben Gordon and Arindam Bhattacharjee and Naftali Kaminski and Panayiotis V. Benos},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={281 - 297}
}
BACKGROUND MicroRNAs (miRNAs) are short, non-coding RNA regulators of protein coding genes. miRNAs play a very important role in diverse biological processes and various diseases. Many algorithms are able to predict miRNA genes and their targets, but their transcription regulation is still under investigation. It is generally believed that intragenic miRNAs (located in introns or exons of protein coding genes) are co-transcribed with their host genes and most intergenic miRNAs transcribed from… CONTINUE READING
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