Features generated for computational splice-site prediction correspond to functional elements

@article{Dogan2007FeaturesGF,
  title={Features generated for computational splice-site prediction correspond to functional elements},
  author={Rezarta Islamaj Dogan and Lise Getoor and W. John Wilbur and Stephen M. Mount},
  journal={BMC Bioinformatics},
  year={2007},
  volume={8},
  pages={410 - 410}
}
Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxiliary signals in the adjacent exons and introns. We previously described a feature generation algorithm (FGA) that is capable of achieving high classification accuracy on human 3' splice sites. In this paper, we extend the splice-site prediction to 5' splice sites and explore the generated features for biologically meaningful… CONTINUE READING