Feasibility of polysaccharide hybrid materials for scaffolds in cartilage tissue engineering: evaluation of chondrocyte adhesion to polyion complex fibers prepared from alginate and chitosan.

@article{Iwasaki2004FeasibilityOP,
  title={Feasibility of polysaccharide hybrid materials for scaffolds in cartilage tissue engineering: evaluation of chondrocyte adhesion to polyion complex fibers prepared from alginate and chitosan.},
  author={Norimasa Iwasaki and Shin-Tarou Yamane and Tokifumi Majima and Yasuhiko Kasahara and Akio Minami and Kazuo Harada and Sachiko Nonaka and Nobuhiko Maekawa and Hiroshi Tamura and Seiichi Tokura and Masamichi Shiono and Kenji Monde and Shin-Ichiro Nishimura},
  journal={Biomacromolecules},
  year={2004},
  volume={5 3},
  pages={828-33}
}
The ideal cell-carrier material for cartilage regeneration should be one that closely mimics the natural environment in a living articular cartilage matrix. In the current study, we considered that alginate-based chitosan hybrid biomaterials could provide excellent supports for chondrocyte adhesion. To test this hypothesis, we investigated the adhesion behavior of rabbit chondrocytes onto an alginate polymer versus the adhesion of the chondrocytes onto some alginate-based chitosan hybrid… CONTINUE READING