Feasibility of noninvasive prenatal testing for common fetal aneuploidies in an early gestational window.

@article{Shi2015FeasibilityON,
  title={Feasibility of noninvasive prenatal testing for common fetal aneuploidies in an early gestational window.},
  author={Xiaolin Shi and Zhitao Zhang and David S Cram and Caixia Liu},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2015},
  volume={439},
  pages={24-8}
}
BACKGROUND Noninvasive prenatal testing (NIPT) by massively parallel sequencing (MPS) of the circulating cell free fetal (cff) DNA during the second trimester of pregnancy is now a frontline test for detecting common fetal chromosomal abnormalities. However, the availability of an earlier test result in the first trimester would enable better clinical management of high-risk pregnancies. The aim of the study was to determine the feasibility of early gestational NIPT. METHODS Plasma DNA… CONTINUE READING