Feasibility of minocycline and doxycycline use as potential vasculostatic therapy for brain vascular malformations: pilot study of adverse events and tolerance.

Abstract

BACKGROUND Tetracyclines may be useful in preventing pathological vascular remodeling, thus decreasing the risk of spontaneous hemorrhage from brain vascular malformations. METHODS Arteriovenous malformation (AVM) and intracranial aneurysm patients undergoing noninvasive management were treated with minocycline or doxycycline (200 mg/day) up to 2 years in… (More)
DOI: 10.1159/000113733

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@article{Frenzel2008FeasibilityOM, title={Feasibility of minocycline and doxycycline use as potential vasculostatic therapy for brain vascular malformations: pilot study of adverse events and tolerance.}, author={Tim Frenzel and Chanhung Z Lee and Helen G. Kim and Nancy J Quinnine and Tomoki Hashimoto and M T Lawton and B. Joseph Guglielmo and Charles E Mcculloch and William L. Young}, journal={Cerebrovascular diseases}, year={2008}, volume={25 1-2}, pages={157-63} }