Feasibility of and rectal dosimetry improvement with the use of SpaceOAR® hydrogel for dose-escalated prostate cancer radiotherapy.

@article{Gysen2014FeasibilityOA,
  title={Feasibility of and rectal dosimetry improvement with the use of SpaceOAR® hydrogel for dose-escalated prostate cancer radiotherapy.},
  author={Kirsten L van Gysen and Andrew Kneebone and Florencia Alfieri and Linxin Guo and Thomas N. Eade},
  journal={Journal of medical imaging and radiation oncology},
  year={2014},
  volume={58 4},
  pages={
          511-6
        }
}
INTRODUCTION The aim of this study was to investigate the feasibility of injecting a temporary spacer between the rectum and the prostate and to quantify the degree of rectal dosimetric improvement that might result. METHODS Ten patients underwent CT and MRI before and after injection of 10 cc of hydrogel and at completion of radiotherapy. Hydrogel was injected under general anaesthetic using a transperineal approach. The primary endpoints were perioperative toxicity and rectal dosimetry (V80… CONTINUE READING
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