Feasibility of a tetracycline-binding method for detecting synovial fluid basic calcium phosphate crystals.

@article{Rosenthal2008FeasibilityOA,
  title={Feasibility of a tetracycline-binding method for detecting synovial fluid basic calcium phosphate crystals.},
  author={Ann Kathryn Rosenthal and Mark Fahey and Claudia M. Gohr and Todd W Burner and Irina Konon and Laureen J Daft and Eric C Mattson and Carol J Hirschmugl and Lawrence M. Ryan and Peter A. Simkin},
  journal={Arthritis and rheumatism},
  year={2008},
  volume={58 10},
  pages={
          3270-4
        }
}
OBJECTIVE Basic calcium phosphate (BCP) crystals are common components of osteoarthritis (OA) synovial fluid. Progress in understanding the role of these bioactive particles in clinical OA has been hampered by difficulties in their identification. Tetracyclines stain calcium phosphate mineral in bone. The aim of this study was to investigate whether tetracycline staining might be an additional or alternative method for identifying BCP crystals in synovial fluid. METHODS A drop of… CONTINUE READING

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