Feasibility of a randomized single-blind crossover trial to assess the effects of the second-generation slow-release dopamine agonists pramipexole and ropinirole on cued recall memory in idiopathic mild or moderate Parkinson’s disease without cognitive impairment

@article{Shepherd2017FeasibilityOA,
  title={Feasibility of a randomized single-blind crossover trial to assess the effects of the second-generation slow-release dopamine agonists pramipexole and ropinirole on cued recall memory in idiopathic mild or moderate Parkinson’s disease without cognitive impairment},
  author={T. A. Shepherd and N. Edelstyn and Laura Longshaw and J. Sim and K. Watts and A. Mayes and Michael Murray and S. Ellis},
  journal={Pilot and Feasibility Studies},
  year={2017},
  volume={4}
}
BackgroundThe aim was to assess the feasibility of a single-centre, single-blind, randomized, crossover design to explore the effects of two slow-release dopamine agonists, ropinirole and pramipexole, on cued recall in Parkinson’s disease.As the design required a switch from the prescribed agonist (pramipexole-to-ropinirole, or ropinirole-to-pramipexole), the primary objectives were to (a) examine the efficacy of processes and procedures used to manage symptoms during the washout period and (b… Expand
1 Citations

References

SHOWING 1-10 OF 42 REFERENCES
An open‐label conversion study of pramipexole to ropinirole prolonged release in Parkinson's disease
  • K. Lyons, R. Pahwa
  • Psychology, Medicine
  • Movement disorders : official journal of the Movement Disorder Society
  • 2009
What motivates Parkinson's disease patients to enter clinical trials?
Another face of placebo: The lessebo effect in Parkinson disease
Second-generation dopamine agonists and recollection impairments in Parkinson's disease.
Parkinson's disease and dopaminergic therapy—differential effects on movement, reward and cognition
Rising to the Challenges of Clinical Trial Improvement in Parkinson's Disease.
The size of a pilot study for a clinical trial should be calculated in relation to considerations of precision and efficiency.
  • J. Sim, M. Lewis
  • Mathematics, Medicine
  • Journal of clinical epidemiology
  • 2012
...
1
2
3
4
5
...