Feasibility of Using the Stable Isotope 25Mg To Study Mg Metabolism in Infants

  title={Feasibility of Using the Stable Isotope 25Mg To Study Mg Metabolism in Infants},
  author={Sally A Schuette and Ekhard E. Ziegler and Steven E. Nelson and Morteza Janghorbani},
  journal={Pediatric Research},
ABSTRACT: The feasibility of using isotopic techniques to study Mg absorption and metabolism was explored in three full-term human infants. 25Mg (98.8 atom %) was administered orally as an in vivo tracer. Fractional 25Mg absorption, isotope retention, endogenous fecal Mg losses, and apparent Mg exchangeable pool size were then determined under three conditions of isotope administration: 1) 20 mg 25Mg, with single feeding; 2) 20 mg 25Mg, distributed over a 24-h period; and 3) 60 mg 25Mg, over a… CONTINUE READING


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