Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid

@inproceedings{Luis2011FeasibilityOP,
  title={Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid},
  author={C A AlvesPedro Luis and Laila R. Abdulhadi Abdullah and Ghania Ait-ghezala and Benoit C. Mouzon and Andrew P Keegan and Fiona Carole Crawford and Michael John Mullan},
  booktitle={International journal of Alzheimer's disease},
  year={2011}
}
We examined the usefulness of brief neuropsychological tests and serum Aβ as a predictive test for detecting MCI/AD in older adults. Serum Aβ levels were measured from 208 subjects who were cognitively normal at enrollment and blood draw. Twenty-eight of the subjects subsequently developed MCI (n = 18) or AD (n = 10) over the follow-up period. Baseline measures of global cognition, memory, language fluency, and serum Aβ(1-42) and the ratio of serum Aβ(1-42)/Aβ(1-40) were significant predictors… CONTINUE READING

Figures, Tables, and Topics from this paper.

Explore Further: Topics Discussed in This Paper

References

Publications referenced by this paper.
SHOWING 1-10 OF 84 REFERENCES

D

N. Ertekin-Taner, L. H. Younkin
  • M. Yager et al., “Plasma amyloid β protein is elevated in late-onset Alzheimer’ disease families,” Neurology, vol. 70, no. 8, pp. 596–606
  • 2008
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

C

L. Abdullah, D. Paris
  • Luis et al., “The influence of diagnosis, intra- and inter-person variability on serum and plasma Aβ levels,” Neuroscience Letters, vol. 428, no. 2-3, pp. 53–58
  • 2007
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

I

J. T. Tschanz, K. A. Welsh-Bohmer
  • Skoog et al., “Dementia diagnoses from clinical and neuropsychological data compared: the cache county study,” Neurology, vol. 54, no. 6, pp. 1290–1296
  • 2000
VIEW 12 EXCERPTS
HIGHLY INFLUENTIAL

N

K. Yaffe, A. Weston
  • R. Graff-Radford et al., “Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline,” Journal of the American Medical Association, vol. 305, pp. 261–266
  • 2011
VIEW 1 EXCERPT

Alzheimer ’ s disease anti - inflammatory prevention trial : design , methods and baseline results

H. C. Chui
  • Alzheimer ’ s Dement
  • 2009

D

C. A. Luis, L. Abdullah
  • Paris et al., “Serum β-amyloid correlates with neuropsychological impairment,” Aging, Neuropsychology, and Cognition, vol. 16, no. 2, pp. 203–218
  • 2009

D

L. Abdullah, C. Luis
  • Paris et al., “High serum Aβ and vascular risk factors in first-degree relatives of Alzheimer’s disease patients,” Molecular Medicine, vol. 15, no. 3-4, pp. 95– 100
  • 2009

Similar Papers

Loading similar papers…