Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions.

@article{Norrholm2015FearLT,
  title={Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions.},
  author={Seth D. Norrholm and Ebony M. Glover and Jennifer Strafford Stevens and Negar Fani and Isaac Galatzer-Levy and Bekh Bradley and Kerry J. Ressler and Tanja Jovanovic},
  journal={International journal of psychophysiology : official journal of the International Organization of Psychophysiology},
  year={2015},
  volume={98 2 Pt 2},
  pages={270-275}
}
Psychophysiological measures of fear expression provide observable intermediate phenotypes of fear-related symptoms. Research Domain Criteria (RDoC) advocate using neurobiological intermediate phenotypes that provide dimensional correlates of psychopathology. Negative Valence Systems in the RDoC matrix include the construct of acute threat, which can be measured on a physiological level using potentiation of the acoustic startle reflex assessed via electromyography recordings of the orbicularis… CONTINUE READING
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