Fear learning and extinction are linked to neuronal plasticity through Rin1 signaling.


The amygdala is known to have a crucial role in both the acquisition and extinction of conditioned fear, but the physiological changes and biochemical mechanisms underlying these forms of learning are only partly understood. The Ras effector Rin1 activates Abl tyrosine kinases and Rab5 GTPases and is highly expressed in mature neurons of the telencephalon… (More)
DOI: 10.1002/jnr.22252