Fc epsilon RI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines.

@article{Toba2003FcER,
  title={Fc epsilon RI and CD22 mRNA are expressed in early B-lineage and myeloid leukemia cell lines.},
  author={Ken Toba and Haruo Hanawa and Minori Sakaue and Kaori Yoshida and Hiromi Itoh and Junjiro Tsuchiyama and Soichi Maruyama and Miwako Narita and Masuhiro Takahashi and Kenichi Watanabe and Yoshifusa Aizawa},
  journal={Leukemia research},
  year={2003},
  volume={27 2},
  pages={
          173-82
        }
}
CD22, one of the important markers for diagnosing B-lineage acute leukemia, was expressed in mature basophil granulocytes. We then investigated the expression of CD22 and other B cell- and basophil-related molecules in 25 human acute leukemia cell lines to find the phenotype of the virtual common progenitor of B and myeloid lineage. Surface and cytoplasmic expressions of antigens were analyzed using a flow cytometer and an essential antibody panel used for diagnosing acute leukemia as well as… CONTINUE READING