Fcγ Receptors and Cross-Presentation in Dendritic Cells

  title={Fcγ Receptors and Cross-Presentation in Dendritic Cells},
  author={S{\'e}bastian Amigorena},
  journal={The Journal of Experimental Medicine},
  pages={f1 - f3}
M. Bevan showed in the mid-seventies that cytotoxic T lymphocyte (CTL) responses may be initiated by antigen-presenting cells that do not express the antigens themselves (1). He called this process cross-priming. The antigen-presenting cells involved in cross-priming must therefore inter-nalize and present antigens to CD8 ϩ T cells in the context of MHC class I molecules. This process is often referred to as " cross-presentation. " Cross-presentation by antigen-presenting cells in vivo results… CONTINUE READING


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