Fcγ Receptor Signaling in Phagocytes

@article{Joshi2006FcRS,
  title={Fc$\gamma$ Receptor Signaling in Phagocytes},
  author={Trupti Joshi and Jonathan P Butchar and Susheela Tridandapani},
  journal={International Journal of Hematology},
  year={2006},
  volume={84},
  pages={210-216}
}
Fcγ receptors are among the best-studied phagocytic receptors. The key features of Fcγ receptor-mediated phagocytosis include phagocytic cup formation by extensive actin cytoskeletal rearrangements, particle engulfment, and the release of proinflammatory mediators such as cytokines and reactive oxygen species. These events are elegantly regulated by the simultaneous engagement of activating and inhibitory Fcγ receptors and by intracellular signaling molecules. Extensive studies in the past… 
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