Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation

@article{Ahmad2016FavorableLO,
  title={Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation},
  author={Ijaz Ahmad and Richard Leblanc and Sandra R Cohen and Silvy Lachance and Thomas Kiss and Guy Sauvageau and Dr. Krishna Chandra Roy and Lambert Busque and J-S Delisle and Nadia M. Bambace and Louis E. Bernard and Waleed Sabry and Jean Roy},
  journal={Bone Marrow Transplantation},
  year={2016},
  volume={51},
  pages={529-535}
}
Despite survival improvement with novel agents and use of autologous hematopoietic stem cell transplantation (HSCT), cure of patients with multiple myeloma (MM) remains anecdotal. Initial observations suggested that chronic GvHD was accompanied by an anti-myeloma effect after myeloablative HSCT, but unfortunately this procedure was hampered by high non-relapse mortality (NRM). To maximize the anti-myeloma effect and minimize NRM, we developed a non-myeloablative (NMA) regimen associated with a… CONTINUE READING
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