Favorable cytogenetic abnormalities in secondary leukemia.

@article{Fenaux1989FavorableCA,
  title={Favorable cytogenetic abnormalities in secondary leukemia.},
  author={Pierre Fenaux and Damien Lucidarme and Jean Luc La{\"i} and Francis Bauters},
  journal={Cancer},
  year={1989},
  volume={63 12},
  pages={
          2505-8
        }
}
The authors report on five patients with secondary leukemia (SL) and one of the "specific" chromosomal rearrangements usually encountered in de novo acute nonlymphoblastic leukemia: inv(16), t(15;17), t(8;21), and t(9;11). They were characterized by solid tumor as the primary malignancy in four of five cases, absence of preleukemic phase in all cases, and myelodysplastic features in one of five cases only. All patients achieved complete remission (CR) with aggressive chemotherapy. Only two… CONTINUE READING
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