Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test.

Abstract

BACKGROUND Autism is accompanied by peripheral and central disorders in the metabolism of serotonin (5-HT). The present study examines plasma dehydroepiandrosterone-sulphate (DHEA-S) and the cortisol/DHEA-S ratio following administration of L-5-hydroxytryptophan (5-HTP), the direct precursor of 5-HT, to autistic patients. METHODS Plasma DHEA-S levels were… (More)

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@article{Croonenberghs2008FaultySI, title={Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test.}, author={J A N Croonenberghs and Kristien Spaas and Annick Wauters and Robert Verkerk and Simon S Scharp{\'e} and Dirk Deboutte and Michael Maes}, journal={Neuro endocrinology letters}, year={2008}, volume={29 3}, pages={385-90} }