Fatty liver largely explains associations of subclinical hypothyroidism with insulin resistance, metabolic syndrome, and subclinical coronary atherosclerosis.

@article{PosadasRomero2014FattyLL,
  title={Fatty liver largely explains associations of subclinical hypothyroidism with insulin resistance, metabolic syndrome, and subclinical coronary atherosclerosis.},
  author={Carlos Posadas-Romero and Esteban Jorge-Galarza and Rosalinda Posadas-S{\'a}nchez and Jorge Acu{\~n}a-Valerio and Juan G Ju{\'a}rez-Rojas and Eric T Kimura-Hayama and Aida X Medina-Urrutia and Guillermo Celestino Cardoso-Salda{\~n}a},
  journal={European journal of endocrinology},
  year={2014},
  volume={171 3},
  pages={319-25}
}
BACKGROUND The association of subclinical hypothyroidism (SCH) with insulin resistance, metabolic syndrome (MS), and coronary atherosclerosis is uncertain. OBJECTIVE To investigate the role of increased intrahepatic fat in the association of SCH with insulin resistance, MS, and coronary atherosclerosis. DESIGN, PATIENTS, AND METHODS We conducted a cross-sectional study in a sample of 753 subjects (46% males) aged 35-70 years with no history of diabetes, renal, hepatic, thyroid, or coronary… CONTINUE READING

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