Fatty liver Shionogi-ob/ob mouse: A new candidate for a non-alcoholic steatohepatitis model.

Abstract

AIM The fatty liver Shionogi (FLS) mouse develops hereditary fatty liver without obesity. The FLS-ob/ob mouse made by transferring the leptin(ob) gene demonstrates several metabolic disorders and marked fat deposition in the liver. The aim was to evaluate which mouse model, the FLS or FLS-ob/ob, is more useful for non-alcoholic steatohepatitis research… (More)
DOI: 10.1111/j.1872-034X.2012.01101.x

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Cite this paper

@article{Sugihara2013FattyLS, title={Fatty liver Shionogi-ob/ob mouse: A new candidate for a non-alcoholic steatohepatitis model.}, author={Takaaki Sugihara and Masahiko Koda and Manabu Kishina and Jun Kato and Shiho Tokunaga and Tomomitsu Matono and Masaru Ueki and Yoshikazu Murawaki}, journal={Hepatology research : the official journal of the Japan Society of Hepatology}, year={2013}, volume={43 5}, pages={547-56} }