Fatty acylation of Wnt proteins.

@article{Nile2016FattyAO,
  title={Fatty acylation of Wnt proteins.},
  author={Aaron H. Nile and Rami N. Hannoush},
  journal={Nature chemical biology},
  year={2016},
  volume={12 2},
  pages={60-9}
}
Wnt proteins are critical regulators of signaling networks during embryonic development and in adult tissue homeostasis. The generation of active Wnt proteins requires their regulated secretion into the extracellular space. Once secreted, Wnts signal through the cell surface via receptor binding on Wnt-receiving cells, a mechanism that is prevalent in stem… CONTINUE READING