Fatty acids as signal transducing molecules: involvement in the differentiation of preadipose to adipose cells.

@article{Amri1994FattyAA,
  title={Fatty acids as signal transducing molecules: involvement in the differentiation of preadipose to adipose cells.},
  author={Ez Z. Amri and G{\'e}rard Ailhaud and Paul Andr{\'e} Grimaldi},
  journal={Journal of lipid research},
  year={1994},
  volume={35 5},
  pages={930-7}
}
Fatty acids are important metabolic substrates for adipose tissue and act, in preadipose cells, as potent inducers of various proteins directly involved in their metabolism. We have investigated the long-term effects of fatty acids on the conversion process of preadipose Ob1771 cells to adipose cells. Chronic exposure of cells to palmitate led, in a dose-dependent manner, to a strong stimulation of cell differentiation; this effect was confined to terminal events whereas fatty acids did not… CONTINUE READING

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