Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats.


This work reports the roles of the concentration of lactate and of fatty acids on lactate uptake by liver cells isolated from fed or 24-h starved rats. Hepatocytes isolated from fed rats released lactate and pyruvate. The addition of lactate shifted the lactate balance from net release to net utilization, with a threshold at approximately 2 mM. Lactate… (More)


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