Fatty acid synthase modulates proliferation, metabolic functions and angiogenesis in hypoxic pulmonary artery endothelial cells.

Abstract

Endothelial dysfunction plays an important role in structural remodeling occurring in the pulmonary vasculature during pulmonary hypertension (PH). Endothelial injury causes apoptosis and activation of endothelial cells. However, some endothelial cells show apoptosis-resistance and later proliferate extensively leading to vascular oculopathy and formation… (More)
DOI: 10.1016/j.ejphar.2017.09.042

Topics

Cite this paper

@article{Singh2017FattyAS, title={Fatty acid synthase modulates proliferation, metabolic functions and angiogenesis in hypoxic pulmonary artery endothelial cells.}, author={Neetu Singh and Himalaya Singh and Kumaravelu Jagavelu and Muhammad Wahajuddin and Kashif Hanif}, journal={European journal of pharmacology}, year={2017}, volume={815}, pages={462-469} }