Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production.

Abstract

UNLABELLED Hepatitis C virus (HCV) is a major human pathogen that causes serious illness, including acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Using a mass spectrometry-based proteomics approach, we have identified 175 proteins from a cell culture supernatant fraction containing the HCV genotype 2a (JFH1) virus, among which fatty… (More)
DOI: 10.1002/hep.22508

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