Fatty acid synthase is expressed mainly in adult hormone-sensitive cells or cells with high lipid metabolism and in proliferating fetal cells.

@article{Kusakabe2000FattyAS,
  title={Fatty acid synthase is expressed mainly in adult hormone-sensitive cells or cells with high lipid metabolism and in proliferating fetal cells.},
  author={Takahiko Kusakabe and Masahiro Maeda and Nobuo Hoshi and Takashi Sugino and Keiichi Watanabe and Toshio Fukuda and Toshimitsu Suzuki},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2000},
  volume={48 5},
  pages={613-22}
}
Animal fatty acid synthase (FAS) is a homodimer protein which synthesizes long-chain fatty acids and is rich in liver, brain, breast, and lung. However, the precise cellular localization of FAS in human tissues has not been elucidated. Immunohistochemistry with a new antibody to human FAS revealed that in adult human tissues FAS is distributed mainly in cells with high lipid metabolism (adipocytes, corpus luteum, hepatocytes, sebaceous glands, and Type II alveolar cells), in hormone-sensitive… CONTINUE READING
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