Fatty acid synthase-associated protein with death domain: a prognostic factor for survival in patients with nasopharyngeal carcinoma.

@article{Li2014FattyAS,
  title={Fatty acid synthase-associated protein with death domain: a prognostic factor for survival in patients with nasopharyngeal carcinoma.},
  author={Jiao Li and Qiuyuan Wen and Lina Xu and Weiyuan Wang and Jiadi Luo and Shuzhou Chu and Guiyuan Xie and Lei Shi and Donghai Huang and Jinghe Li and Songqing Fan},
  journal={Human pathology},
  year={2014},
  volume={45 12},
  pages={2447-52}
}
Fatty acid synthase-associated protein with death domain (FADD) is a key adaptor protein that bridges a death receptor (eg, death receptor 5) to caspase 8 to form the death-inducing signaling complex during apoptosis. The expression and prognostic impact of FADD in nasopharyngeal carcinoma (NPC) have not been well studied. This study focused on detecting FADD expression and analyzing its prognostic impact on NPC. FADD expression was assessed on pretreatment tumor tissues of 248 cases of NPC… CONTINUE READING