Fatty acid specificity of the lysosomal acid cholesterol esterase in intact human arterial smooth muscle cells.

@article{Slotte1988FattyAS,
  title={Fatty acid specificity of the lysosomal acid cholesterol esterase in intact human arterial smooth muscle cells.},
  author={J Peter Slotte and Edwin L. Bierman},
  journal={Biochimica et biophysica acta},
  year={1988},
  volume={958 2},
  pages={308-12}
}
The fatty-acid specificity of the lysosomal cholesterol esterase was examined in cultured human arterial smooth muscle cells. The lysosomal compartment of cultured cells was enriched with cholesteryl esters by incubation of cells with 0.2 mg/ml low-density lipoprotein and 50 microM chloroquine for 24 h. The hydrolysis of cholesteryl esters was subsequently… CONTINUE READING