Fatty acid specificity of hormone-sensitive lipase. Implication in the selective hydrolysis of triacylglycerols.

@article{Raclot2001FattyAS,
  title={Fatty acid specificity of hormone-sensitive lipase. Implication in the selective hydrolysis of triacylglycerols.},
  author={Thierry Raclot and C. G. Patrik Holm and Dominique Langin},
  journal={Journal of lipid research},
  year={2001},
  volume={42 12},
  pages={
          2049-57
        }
}
The selective mobilization of fatty acids from white fat cells depends on their molecular structure, in particular the degree of unsaturation. The present study was designed to examine if the release of fatty acids by hormone-sensitive lipase (HSL) in vitro i) is influenced by the amount of unsaturation, ii) depends on the temperature, and iii) could explain the selective pattern of fatty acid mobilization and notably the preferential mobilization of certain highly unsaturated fatty acids… CONTINUE READING

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